Circulating levels of tissue inhibitor of metalloproteinase 3, a protein with inhibitory effects on angiogenesis, are increased in pre-eclampsia.
Ana C T PaleiJuliana de O CruzJoão Leandro ChaguriJose Carlos PeracoliMariana Romao-VeigaVanessa R Ribeiro-VasquesRicardo de Carvalho CavalliPriscila Rezeck NunesMarcelo Rizzatti LuizonValéria Cristina SandrimPublished in: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2022)
Circulating TIMP-3 concentration is increased in women with pre-eclampsia compared with healthy pregnant women, and it is positively correlated with plasma MMP-2 and TIMP-1 concentrations in pre-eclampsia.