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Cutaneous SCC with orbital invasion: case series.

Mirjam NägeliJ ManganaK ChaloupkaReinhard Dummer
Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2021)
Cutaneous squamous cell carcinoma (cSCC) is the most common tumour entity that grows secondarily into the orbital area, while basal cell carcinoma (BCC) is the most common periocular and eyelid tumour. Diagnostic delays are common and may increase post-treatment complications. The therapy is challenging and must be discussed at an interdisciplinary tumour board. We discuss four cases of cSCC with orbital invasion treated with immune-checkpoint inhibitors with variable responses.
Keyphrases
  • squamous cell carcinoma
  • basal cell carcinoma
  • cell migration
  • stem cells
  • radiation therapy
  • combination therapy
  • lymph node metastasis
  • replacement therapy
  • newly diagnosed
  • bone marrow
  • cell therapy
  • smoking cessation