Antibodies to FXa and thrombin in patients with SLE differentially regulate C3 and C5 cleavage.
Thomas C R McDonnellRaj AmarnaniCarina SpicerHajar JbariCharis PericleousValentina A SpiteriChris WincupBahar Artim-EsenIan MackieMarina BottoAnisur RahmanIan GilesPublished in: Lupus science & medicine (2022)
We propose a novel method of complement regulation in patients with SLE±APS whereby aFXa and aThr IgG may have differential effects on complement activation.