Association of the neonatal Fc receptor promoter variable number of tandem repeat polymorphism with immunoglobulin response in patients with chronic inflammatory demyelinating polyneuropathy.

Anna Lena FisseEmelie SchäferAlina HiekeMaximilian SchröderRafael KlimasJil BrüngerSophie HuckemannThomas GrüterMelissa SgodzaiChristiane Schneider-GoldRalf GoldHuu Phuc NguyenKalliopi PitarokoiliJeremias MotteLarissa Arning

Published in: European journal of neurology (2024)

The VNTR 2/3 genotype is associated with the administration of SCIg, possibly reflecting a greater benefit from SCIg due to more constant immunoglobulin levels without lower IVIg levels between the treatment circles. Also, the greater need for second-line treatment in VNTR 2/3 patients could be an indirect sign of a lower response to immunoglobulins.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
gene expression
dna methylation
peritoneal dialysis
transcription factor
combination therapy
binding protein
smoking cessation