Population pharmacokinetics of tenofovir, emtricitabine and intracellular metabolites in transgender women.

Asama TanaudommongkonAyyappa ChaturvedulaCraig W HendrixEdward J FuchsEugenie ShiehRahul P BakshiMark A Marzinke

Published in: British journal of clinical pharmacology (2022)

PopPK models of TFV, emtricitabine and intracellular metabolites in TGW were established. Dose simulations revealed that TGW should be treated for at least 2 weeks to have comparable exposures to CGM.

Keyphrases

ms ms
reactive oxygen species
polycystic ovary syndrome
air pollution
molecular dynamics
single cell
pregnancy outcomes
antiretroviral therapy
hiv testing
type diabetes
adipose tissue
pregnant women
breast cancer risk
insulin resistance
hepatitis c virus
preterm birth