Metabolomics Reveals Molecular Signatures for Psoriasis Biomarkers and Drug Targets Discovery.

Qian SongYing ChenJianQing MaWei ZhouJunYan SongChunFu WuJie Liu

Published in: Clinical, cosmetic and investigational dermatology (2023)

In this study, we identified 10 differential metabolites as possible potential combinatorial biomarkers for the diagnosis of psoriasis. 12 metabolic pathways were significantly enriched that may be closely related to the occurrence and development of psoriasis. Three proteins, ESR1, OPRM1, and HSD11B1, were identified as possible potential therapeutic targets for psoriasis.

Keyphrases

atopic dermatitis
risk assessment
small molecule
mass spectrometry
human health
emergency department
gene expression
high throughput
genome wide
single molecule
drug induced
adverse drug