Disparities in cancer genetics care by race/ethnicity among pan-cancer patients with pathogenic germline variants.
Ying L LiuAnna MaioYelena KemelErin E Salo-MullenMargaret SheehanPrince Ray TejadaMagan TrottierAngela G ArnoldMegan Harlan FleischutAlicia J LathamMaria I CarloYonina R Murciano-GoroffMichael F WalshDiana MandelkerNikita MehtaChaitanya BandlamudiKanika S AroraAhmet ZehirMichael F BergerDavid B SolitCarol AghajanianLuis A DiazMark E RobsonCarol L BrownKenneth OffitJada G HamiltonZsofia K StadlerPublished in: Cancer (2022)
Genetic testing is becoming an important part of cancer care, and we wanted to see if genetics care was different between individuals of different backgrounds. We studied 15,775 diverse patients with cancer who had genetic testing using a test called MSK-IMPACT that was covered by research funding. Clinically important genetic findings were high in all groups. However, Black patients were less likely to get recommended counseling compared to White patients. Even after removing many roadblocks, non-White and especially Black patients were less likely to get recommended genetics care, which may affect their cancer treatments and families.
Keyphrases
- end stage renal disease
- ejection fraction
- healthcare
- chronic kidney disease
- newly diagnosed
- palliative care
- prognostic factors
- peritoneal dialysis
- quality improvement
- oxidative stress
- copy number
- pain management
- dna damage
- patient reported outcomes
- human immunodeficiency virus
- smoking cessation
- hiv infected
- men who have sex with men