Clinical application of targeted next-generation sequencing in fetuses with congenital heart defect.

P HuF QiaoY WangL MengX JiC LuoT XuR ZhouJ ZhangB YuL WangT WangQ PanD MaD LiangZhengfeng Xu

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2018)

Targeted NGS in fetuses with isolated and non-isolated CHD achieved a high diagnostic yield in our cohort, with an acceptable turnaround time for the prenatal setting. Our results have important implications for clinical management and genetic counseling. Copyright © 2018 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

cancer therapy
gestational age
copy number
pregnant women
genome wide
smoking cessation
systematic review
hiv testing
hepatitis c virus