Correlates of protection and determinants of SARS-CoV-2 breakthrough infections 1 year after third dose vaccination.

Carla Martín PérezRuth AguilarAlfons JiménezGemma SalmerónMar CanyellesRocío RubioMarta VidalInocencia CuambaDiana BarriosNatalia DíazRebeca SantanoPau SerraPere SantamariaLuis IzquierdoAntoni TrillaAnna VilellaSonia BarrosoMarta TortajadaAlberto L García-BasteiroGemma MoncunillCarlota Dobano

Published in: BMC medicine (2024)

Data show that IgG and IgA induced by vaccines against the original strain or by hybrid immunization are valid correlates of protection against Omicron BA.1 despite immune escape and support the benefits of heterologous vaccination regimens to enhance antibodies and the prioritization of booster vaccination in individuals without recent infections.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
data analysis
deep learning
artificial intelligence