3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma.

Nicole IoannouJinyuan LuoMengqi QinMatteo Di LucaEssyrose MathewAristides D TagalakisDimitrios A Lamprou Cynthia Yu-Wai-Man

Published in: The Journal of pharmacy and pharmacology (2023)

The PCL-CS-5-FU implant was biocompatible and degradable with a significant effect in suppressing fibroblast contractility. The PCL-CS-5-FU implant could be used as a sustained release drug implant, replacing the need for repeated 5-FU injections in clinic, to prevent conjunctival fibrosis after glaucoma surgery.

Keyphrases

soft tissue
minimally invasive
primary care
emergency department
coronary artery bypass
drug delivery
coronary artery disease
acute coronary syndrome
platelet rich plasma
atrial fibrillation
electronic health record
drug induced
smooth muscle
optical coherence tomography