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Management of de novo metastatic hormone-sensitive prostate cancer: A comprehensive report of a single-center experience.

Sunny GuinBobby K LiawTomi JunKristin AyersBonny PatelTimmy O'ConnellMatthew DeitzMichael KleinTommy MullaneyTony PrenticeScott NewmanMarc FinkXiang ZhouEric E SchadtRong ChenWilliam K Oh
Published in: PloS one (2022)
Real world data demonstrated a shorter duration of treatment with docetaxel than NHAs, reflecting the time-limited nature of docetaxel regimens compared to the treat-till-progression approach of NHAs. While TTNT was generally longer for NHAs than docetaxel, some docetaxel-treated patients achieved significant periods of time off treatment. In addition, the depth of PSA response following combination treatment may hold prognostic value for mHSPC outcomes.
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