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Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease.

Alexa R WeingardenByron P Vaughn
Published in: Gut microbes (2017)
Inflammatory bowel disease (IBD) is a complex set of diseases that lead to chronic inflammation in the gastrointestinal tract. Although the etiology of IBD is not fully understood, it is well-known that the intestinal microbiota is associated with the development and maintenance of IBD. Manipulation of the gut microbiota, therefore, may represent a target for IBD therapy. Fecal microbiota transplantation (FMT), where fecal microbiota from a healthy donor is transplanted into a patient's GI tract, is already a successful therapy for Clostridium difficile infection. FMT is currently being explored as a potential therapy for IBD as well. In this review, the associations between the gut microbiota and IBD and the emerging data on FMT for IBD will be discussed.
Keyphrases
  • ulcerative colitis
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  • machine learning
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  • mesenchymal stem cells
  • climate change
  • human health