Login / Signup

Melioidosis DS rapid test: A standardized serological dipstick assay with increased sensitivity and reliability due to multiplex detection.

Gabriel E WagnerEsther Föderl-HöbenreichKaroline AssigMichaela LippAndreas BernerChristian KohlerSabine LichteneggerJulia StiehlerWisansanee KaroonboonyananNida ThanapattarapairojChidchanok PromkongSirikamon KoosakulnirandPanjaporn ChaichanaRalf EhrichtAnne-Marie GadHans H SöffingSusanna J DunachieNarisara ChantratitaIvo Steinmetz
Published in: PLoS neglected tropical diseases (2020)
Our dipstick rapid test represents an inexpensive, standardized and simple diagnostic tool with an improved serodiagnostic performance due to multiplex detection. Each additional band on the test strip makes a false-positive result more unlikely, contributing to its reliability. Future prospective studies will seek to validate the gain in sensitivity and specificity of our multiplex rapid test approach in different melioidosis patient cohorts.
Keyphrases
  • loop mediated isothermal amplification
  • real time pcr
  • sensitive detection
  • high throughput
  • case report
  • label free
  • single cell
  • case control