Association between PRKG1 gene and gene-environment interactions with pediatric asthma.

Jun LiuBing WeiYuxuan ZhangYuan YouYanjie Zhi

Published in: The Journal of asthma : official journal of the Association for the Care of Asthma (2024)

gene was associated with susceptibility to childhood asthma, and C allele is a protective factor. The haplotype CAGA had a protective effect against asthma risk and TGAC was linked to the high risk of developing asthma. Moreover, the interaction of rs7897633, allergen exposure, residence, and ETS exposure conferred susceptibility to childhood asthma.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
genome wide
copy number
helicobacter pylori
transcription factor
young adults
dna methylation
childhood cancer