Comparative efficacy of glucose-lowering medications on body weight and blood pressure in patients with type 2 diabetes: A systematic review and network meta-analysis.

Apostolos Tsapas Thomas Karagiannis Panagiota Kakotrichi Ioannis Avgerinos Chrysanthi Mantsiou Georgios Tousinas Apostolos Manolopoulos Aris Liakos Konstantinos Malandris David R Matthews Apostolos Tsapas

Published in: Diabetes, obesity & metabolism (2021)

Semaglutide and SGLT-2 inhibitors conferred reductions both in body weight and blood pressure that were sustainable for over 1 year of treatment. These agents may be preferable treatment options for patients with type 2 diabetes who are overweight/obese and/or hypertensive.

Keyphrases

body weight
blood pressure
hypertensive patients
weight loss
heart rate
blood glucose
adipose tissue
metabolic syndrome
type diabetes
physical activity
bariatric surgery
body mass index
combination therapy
insulin resistance