Sirolimus versus tacrolimus for systemic lupus erythematosus treatment: results from a real-world CSTAR cohort study.
Nan JiangMengtao LiHongfeng ZhangXinwang DuanXiaofeng LiYongfei FangHongbin LiPingting YangHui LuoYanhong WangLiying PengJiuliang ZhaoChanyuan WuQian WangXinping TianYan ZhaoXiaofeng ZengPublished in: Lupus science & medicine (2022)
Overall, sirolimus was as effective as tacrolimus in the treatment of SLE. Sirolimus had better effects on serological improvement and glucocorticoid tapering. Sirolimus was well tolerated in patients with SLE.