Integrative network analysis reveals biological pathways associated with Williams syndrome.

Ryo KimuraVivek SwarupKiyotaka TomiwaMichael J GandalNeelroop N ParikshakYasuko FunabikiMasatoshi NakataTomonari AwayaTakeo KatoKei IidaShin OkazakiKanae MatsushimaToshihiro KatoToshiya MuraiToshio HeikeDaniel H GeschwindMasatoshi Hagiwara

Published in: Journal of child psychology and psychiatry, and allied disciplines (2018)

Dysregulation of the mRNA/miRNA network involving genes outside of the 7q11.23 region is likely related to the complex phenotypes observed in WS patients.

Keyphrases

network analysis
end stage renal disease
ejection fraction
chronic kidney disease
genome wide
gene expression
dna methylation