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Evaluation of SNPs associated with mammographic density in European women with mammographic density in Asian women from South-East Asia.

Shivaani MariapunWeang Kee HoMikael ErikssonMei Chee TaiNur Aishah Mohd TaibCheng Har YipKartini RahmatJingmei LiMikael HartmanPer HallDouglas F EastonSara LindstromSoo-Hwang Teo
Published in: Breast cancer research and treatment (2023)
Our study confirms the associations of 21 SNPs (19/55 or 34.5% out of all known MD loci identified in women of European ancestry) with area and/or volumetric densities in Asian women, and further supports the evidence of a shared genetic basis through common genetic variants for MD and breast cancer risk.
Keyphrases
  • breast cancer risk
  • genome wide
  • polycystic ovary syndrome
  • pregnancy outcomes
  • molecular dynamics
  • type diabetes
  • gene expression
  • genome wide association
  • cervical cancer screening
  • dna methylation
  • copy number