Association of NOS3 and ANGPT2 Gene Polymorphisms with Survival in Patients with Hepatocellular Carcinoma Receiving Sorafenib: Results of the Multicenter Prospective INNOVATE Study.
Stefano CascinuGiorgia MarisiVincenzo DadduzioLaura GramantieriLuca FaloppiPaola UliviFrancesco Giuseppe FoschiEmiliano TamburiniCaterina VivaldiMario Domenico RizzatoLuca IelasiMatteo CanaleFabio ContiBritt RudnasLorenzo FornaroNicola SilvestrisMarianna SillettaGiovanni Gerardo CardellinoSara LonardiFrancesca FornariGiulia OrsiGiulia RovestiVittorina ZagonelStefano CascinuMario ScartozziPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
The INNOVATE study met the primary endpoint, confirming that patients with advanced HCC with NOS3 rs2070744 CC/CT genotypes had a better prognosis with respect to TT genotype patients.