Prevalence of sleep apnoea and capnographic detection of nocturnal hypoventilation in amyotrophic lateral sclerosis.

Matthias BoentertChristian GlatzCornelia HelmleAngelika OkegwoPeter Young

Published in: Journal of neurology, neurosurgery, and psychiatry (2017)

In ALS, sleep apnoea is common and often accompanies NH. It is mainly obstructive, and central apnoea appears to be clinically irrelevant. Polygraphy or oxymetry alone are not sufficient to uncover NH. Combination of EMBE and t<90% may increase sensitivity, but transcutaneous capnography is strongly recommended for reliable detection of NH in patients with ALS.

Keyphrases

positive airway pressure
obstructive sleep apnea
sleep apnea
room temperature
sleep quality
loop mediated isothermal amplification
physical activity
real time pcr
label free
amyotrophic lateral sclerosis
perovskite solar cells
risk factors
blood pressure
depressive symptoms