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Network Pharmacology Study of Bioactive Components and Molecular Mechanisms of the Glycoside Fraction from Picrorhiza scrophulariiflora Against Experimental Colitis.

Peigen WuChurui ChangGuanglin ZhuLixiang ZhaiXu ZhangQiuchan HuanZhengxian GaoHuan DengYue LiangHai-Tao Xiao
Published in: Drug design, development and therapy (2023)
The therapeutic effect of GPS extract on colitis is related to PI3K/Akt and MAPK pathways, which is a promising remedy for colitis therapy.
Keyphrases
  • pi k akt
  • signaling pathway
  • cell proliferation
  • cell cycle arrest
  • ulcerative colitis
  • oxidative stress
  • anti inflammatory
  • cell death