Clinically Significant Changes in the 17- and 6-Item Hamilton Rating Scales for Depression: A STAR*D Report.
Augustus John RushCharles SouthShailesh JainRaafae AghaMingxu ZhangShristi ShresthaZershana KhanMudasar HassanMadhukar H TrivediPublished in: Neuropsychiatric disease and treatment (2021)
A 4-6 point change in the HRSD17 is clinically meaningful; a 7-12 point change is clinically substantial. For the HRSD6, analogous estimates were 2-3 and 4-7 point changes, respectively.