Regulation of the Inflammatory Synovial Fibroblast Phenotype by Metastasis-Associated Lung Adenocarcinoma Transcript 1 Long Noncoding RNA in Obese Patients With Osteoarthritis.
Dominika E NanusSusanne N WijesingheMark J PearsonMarina R HadjicharalambousAlex RosserEdward T DavisMark A LindsaySimon W JonesPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
Synovial fibroblasts from obese patients with hip OA exhibit an inflammatory phenotype. MALAT1 lncRNA may mediate joint inflammation in obese OA patients.
Keyphrases
- obese patients
- bariatric surgery
- long noncoding rna
- gastric bypass
- roux en y gastric bypass
- oxidative stress
- end stage renal disease
- weight loss
- knee osteoarthritis
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- adipose tissue
- extracellular matrix
- patient reported
- total hip arthroplasty
- single cell