Potentiation of spinal glutamatergic response in the neuron-glia interactions underlies the intrathecal IL-1β-induced thermal hyperalgesia in rats.

Chun-Sung SungZhi-Hong WenChien-Wei FengChun-Hong ChenShi-Ying HuangNan-Fu ChenWu-Fu ChenChih-Shung Wong

Published in: CNS neuroscience & therapeutics (2017)

The enhanced glutamatergic response and neuron-glia interaction potentiate the intrathecal IL-1β-activated P-p38/iNOS/NO signaling and thermal hyperalgesia.

Keyphrases

neuropathic pain
spinal cord
high glucose
spinal cord injury
nitric oxide
oxidative stress