Partial Personalization of Medical Treatment Decisions: Adverse Effects and Possible Solutions.
Christopher WeyantMargaret L BrandeauPublished in: Medical decision making : an international journal of the Society for Medical Decision Making (2021)
Selecting personalized treatments for patients should be done in a way that does not decrease expected population-level health outcomes and does not increase their variance, thereby resulting in worse risk-adjusted, population-level health outcomes compared with treatment selection with no personalization. Our method can be used to ensure this, thereby helping patients realize the benefits of treatment personalization without the potential harms.