Pretreatment with Antioxidants Augments the Acute Arterial Vasoconstriction Caused by Diesel Exhaust Inhalation.

Cora S SackKaren L JansenKristen E CosselmanCarol A TrengaPat L StapletonJason AllenAlon PeretzCasey OlivesJoel Daniel Kaufman

Published in: American journal of respiratory and critical care medicine (2017)

We confirmed that short-term exposure to diesel exhaust in healthy subjects is associated with acute vasoconstriction in a conductance artery and found suggestive evidence of involvement of nociception and renin-angiotensin systems in this effect. Pretreatment with an antioxidant regimen increased vasoconstriction.

Keyphrases

liver failure
respiratory failure
particulate matter
aortic dissection
drug induced
angiotensin converting enzyme
oxidative stress
angiotensin ii
hepatitis b virus
anti inflammatory
extracorporeal membrane oxygenation
air pollution
mechanical ventilation
acute respiratory distress syndrome