Effects of Alginic Acid on the Porcine Granulosa Cells and Maturation of Porcine Oocytes.

Jinjie WangYankun LiHuan YuanShengjie ShiLutong ZhangGongshe YangWei-Jun PangLei GaoChuanjiang CaiGuiyan Chu

Published in: Molecular nutrition & food research (2023)

These findings suggest that 20 µM AA is toxic to sow reproduction by interfering with estrogen production, oxidative stress, mitochondria-mediated apoptosis, autophagy in GCs of sows, and oocyte maturation.

Keyphrases

induced apoptosis
oxidative stress
endoplasmic reticulum stress
cell death
cell cycle arrest
signaling pathway
dna damage
ischemia reperfusion injury
diabetic rats
polycystic ovary syndrome
estrogen receptor
type diabetes
metabolic syndrome
cell proliferation
skeletal muscle