Obesity and low-grade inflammation increase plasma follistatin-like 3 in humans.

Claus BrandtMaria PedersenAnders RinnovAnne S AndreasenKirsten MøllerPernille HojmanBente K PedersenPeter Plomgaard

Published in: Mediators of inflammation (2014)

Plasma fstl3 is increased in obese subjects and associated with fat mass and low-grade inflammation. Furthermore, TNF-α increased plasma fstl3, suggesting that TNF-α is one of the inflammatory drivers of increased systemic levels of fstl3.

Keyphrases

low grade
high grade
oxidative stress
adipose tissue
metabolic syndrome
weight loss
rheumatoid arthritis
type diabetes
insulin resistance
obese patients
skeletal muscle