Pseudo-continuous arterial spin labelling shows high diagnostic performance in the detection of postoperative residual lesion in hyper-vascularised adult brain tumours.
Clara CohenBruno Law-YeDidier DormontDelphine LeclercqLaurent CapelleMarc SansonDamien GalanaudNadya PyatigorskayaPublished in: European radiology (2020)
• Evaluation of postoperative residual lesion in the case of brain tumours is an imaging challenge. • This prospective monocentric study showed that increased normalised cerebral blood flow assessed by pseudo-continuous arterial spin labelling (pCASL) correlates well with the presence of a residual tumour in the case of hyper-vascular tumour diagnosed on preoperative MRI. • Qualitative and quantitative pCASL is an informative sequence for hyper-vascular residual tumour, especially if acquired more than 48 h after brain tumour surgery, when contrast enhancement can give ambiguous results due to blood-brain barrier disruption.
Keyphrases
- blood brain barrier
- cerebral ischemia
- patients undergoing
- white matter
- resting state
- cerebral blood flow
- high resolution
- minimally invasive
- density functional theory
- magnetic resonance imaging
- magnetic resonance
- room temperature
- systematic review
- single molecule
- coronary artery disease
- acute coronary syndrome
- multiple sclerosis
- mass spectrometry
- diffusion weighted imaging