A randomized clinical trial of age and genotype-guided tacrolimus dosing after pediatric solid organ transplantation.

Sandar MinTanya PapazMyriam Lafreniere-RoulaNadya NalliHartmut GrasemannSteven M SchwartzBinita M KamathVicky NgRulan S ParekhCedric ManlhiotSeema Mital

Published in: Pediatric transplantation (2018)

CYP3A5 genotype-guided dosing stratified by age resulted in earlier attainment of therapeutic tacrolimus concentrations and fewer out-of-range concentrations.

Keyphrases

stem cells
cell therapy
young adults
mesenchymal stem cells
childhood cancer