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Reciprocal Interactions between Fibroblast and Pancreatic Neuroendocrine Tumor Cells: Putative Impact of the Tumor Microenvironment.

Thomas CunyPeter M van KoetsveldGrégoire MondielliFadime DoganWouter W de HerderAnne BarlierLeo J Hofland
Published in: Cancers (2022)
Fibroblasts in the TME of PNENs represent a target of interest, the stimulatory effect of which over PNENs is mitigated by the mTOR inhibitor everolimus.
Keyphrases
  • cell proliferation
  • extracellular matrix
  • wound healing