Noninvasive Detection of Ischemic Vascular Damage in a Pig Model of Liver Donation After Circulatory Death.

Katherine J I EmberFiona HuntLauren E JamiesonJohn M HallettHannah EsserTimothy James KendallR Eddie CluttonRachael GregsonKaren FauldsStuart John ForbesGabriel C OniscuColin J Campbell

Published in: Hepatology (Baltimore, Md.) (2021)

Raman spectroscopy is an effective tool for detecting microvascular damage which could assist the decision to use marginal livers for transplantation. Reducing the volume of circulating blood before circulatory arrest in DCD may help reduce microvascular damage.

Keyphrases

raman spectroscopy
oxidative stress
extracorporeal membrane oxygenation
cell cycle
ischemia reperfusion injury
cell therapy
decision making
mesenchymal stem cells