Evaluation of anti-inflammatory activity of kaurenol: Experimental evaluation and mechanistic insights.
Ricardo Andrade FurtadoSamir Anis RossSilvio de Almeida-JuniorRafael Paranhos de MendonçaCristiane Martins Rodrigues BernardesMauro Nogueira da SilvaKarina Furlani ZoccalLúcia Helena FaccioliA N D Jairo Kenupp BastosPublished in: Fundamental & clinical pharmacology (2023)
The anti-inflammatory activity was associated with the regulation of NO release and probably with the regulation of mediators, such as serotonin and prostaglandin in vascular permeability, as well as by being associated with the regulation of IL-6 and IL-10. Kaurenol display anti-inflammatory activity but has no analgesic activity.