Prognostic factors of methotrexate-associated lymphoproliferative disorders associated with rheumatoid arthritis and plausible application of biological agents.

Takayuki KatsuyamaKen-Ei SadaMinglu YanSonia ZeggarSumie HiramatsuYoshia MiyawakiKeiji OhashiMichiko MorishitaHaruki WatanabeEri KatsuyamaMariko Takano-NarazakiNoriko Toyota-TatebeKatsue Sunahori-WatanabeTomoko KawabataKohei MiyakeToru KiguchiJun Wada

Published in: Modern rheumatology (2016)

Peripheral blood EBV-DNA positivity is a potential prognostic marker of better outcome in MTX-LPD. Biological agents could be an option for the treatment of RA patients with MTX-LPD.

Keyphrases

prognostic factors
rheumatoid arthritis
peripheral blood
epstein barr virus

disease activity
ankylosing spondylitis
diffuse large b cell lymphoma
interstitial lung disease

circulating tumor
high dose
cell free
systemic sclerosis

combination therapy
climate change
replacement therapy
smoking cessation