Novel mutations in actionable breast cancer genes by targeted sequencing in an ethnically homogenous cohort.

Hosneara AkterNasima SultanaNazrana MartuzaAaysha SiddiquaNushrat Jahan DityMd Atikur RahamanBisan SamaraAhmed SayeedMohammed BasiruzzamanMohammad Mizanur RahmanMd Rashidul HoqMd Robed AminMd Abdul BaquiMarc Woodbury-SmithK M Furkan UddinSyed S IslamRayhana AwwalBakhrom K BerdievMohammed Uddin

Published in: BMC medical genetics (2019)

This is the first genetic study of BC predisposition genes in this population, implies that genetic screening through targeted sequencing can detect clinically significant and actionable BC-relevant mutations.

Keyphrases

genome wide
single cell
cancer therapy
dna methylation
copy number
bioinformatics analysis
gene expression
young adults