Performance of preferentially expressed antigen in melanoma (PRAME) immunohistochemistry for metastatic melanoma in cytology specimens.

Mohammed SaadRichard L CantleyWei HaoZixi WangDafydd ThomasLiron Pantanowitz Xiaobing Jin

Published in: Diagnostic cytopathology (2024)

PRAME is a useful marker for the diagnosis of melanoma in cytology material, but it is less sensitive than SOX10. PRAME is also expressed in other nonmelanocytic tumors which limits its specificity.

Keyphrases

fine needle aspiration
ultrasound guided
high grade
skin cancer
stem cells
transcription factor
basal cell carcinoma