Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins.

Alaina H WilletJun-Song ChenLiping RenKathleen L Gould

Published in: bioRxiv : the preprint server for biology (2023)

Fission yeast long-tailed myosin-1 binds Ank1. Ank1 ankyrin repeats associate with the Myo1 lever arm and Ank1 acidic tail binds the Myo1 TH1 domain to inhibit Myo1 membrane binding. Ank1 orthologs exists in budding yeast (Ank1) and humans (OSTF1).

Keyphrases

binding protein
saccharomyces cerevisiae
transcription factor