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Adoption of Advanced Chemometric Methods for Determination of Pyridoxine HCl, Cyclizine HCl, and Meclizine HCl in Presence of Related Impurities: A Comparative Study.

Ahmed Sayed SaadMohammed E DrazIbrahim A NaguibHala E ZaazaaAdel S LashienFatma F Abdallah
Published in: Journal of AOAC International (2021)
Novel optimizations of the widely-used chemometric models; application of comparative study between the suggested methods; application of OPLS pre-processing methods; quantitative determination of pyridoxine HCl, cyclizine HCl and meclizine HCl; checking the predictive power of developed chemometric models; analysis of the active ingredients in their pharmaceutical dosage forms.
Keyphrases
  • high resolution
  • electronic health record
  • mass spectrometry