Molecular characterisation of metanephric adenomas beyond BRAF: genetic evidence for potential malignant evolution.

Emily ChanBradley A StohrNicole A CroomSoo-Jin ChoKaruna GargMegan L TroxellJohn P HigginsGregory R Bean

Published in: Histopathology (2020)

Although the vast majority of MAs show indolent behaviour, rare pathogenic alterations can occur in conventional MAs in addition to BRAF. Molecular profiling of a case with aggressive clinical and pathological features shows genetic evidence for malignant evolution in MAs.

Keyphrases

genome wide
metastatic colorectal cancer
copy number
single molecule
single cell
risk assessment
hodgkin lymphoma