Valproate in status epilepticus: Correlation between loading dose, serum levels, and clinical response.
Sergiu VijialaPascal AndréThierry BuclinLaurent A DecosterdAndrea O RossettiJan NovyPublished in: European journal of neurology (2022)
A high loading dose (>30 mg/kg) is not associated with a greater response rate in patients with SE. Therefore, it seems to bring little benefit. If confirmed in further studies, a dosage of 25-30 mg/kg appears adequate in SE.
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