Identification of TNF-α as Major Susceptible Risk Locus for Vitiligo: A Systematic Review and Meta-Analysis Study in the Asian Population.
Tithi DuttaSambuddha SenguptaSuchismita AdhyaArpan SahaDebmalya SenguptaRitisri MondalSwarnadru NaskarSamsiddhi BhattacharjeeMainak SenguptaPublished in: Dermatology (Basel, Switzerland) (2024)
Our study constitutes the first comprehensive meta-analysis of candidate gene-based association studies reported in the whole of the Asian population, followed by an in silico analysis of the vitiligo-associated variant. According to the findings of our study, TNF-α single nucleotide variant rs1800629G>A has a risk association, potentially contributing to vitiligo pathogenesis in the Asian population.