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Molecular iodine exerts antineoplastic effects by diminishing proliferation and invasive potential and activating the immune response in mammary cancer xenografts.

Irasema MendietaRosa E Nuñez-AnitaMario Nava-VillalbaXóchitl Zambrano-EstradaEvangelina Delgado-GonzálezBrenda AnguianoCarmen Aceves
Published in: BMC cancer (2019)
I2 decreases the invasive potential of a triple negative basal cancer cell line, and under in vivo conditions the oral supplement of this halogen activates the antitumor immune response, preventing progression of xenografts from laminal and basal mammary cancer cells. These effects allow us to propose iodine supplementation as a possible adjuvant in breast cancer therapy.
Keyphrases
  • immune response
  • papillary thyroid
  • cancer therapy
  • signaling pathway
  • early stage
  • dendritic cells
  • toll like receptor
  • lymph node metastasis
  • human health
  • computed tomography