Transcatheter aortic valve replacement and percutaneous coronary intervention versus surgical aortic valve replacement and coronary artery bypass grafting in patients with severe aortic stenosis and concomitant coronary artery disease: A systematic review and meta-analysis.
Rafail A KotroniasJonathan H BrayRoberto ScarsiniSkanda RajasundaramDimitrios Terentes-PrintziosGiovanni L De MariaRajesh K KharbandaMamas A MamasRodrigo BagurAdrian P BanningPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2020)
Our analysis suggests that a percutaneous transcatheter approach confers similar outcomes compared to a surgical approach in patients with severe AS and CAD. However, our findings are based on low quality studies and should serve as hypothesis generating. In the absence of adequately powered studies yielding high level evidence, individualized decision making should be based on surgical risk assessment.
Keyphrases
- aortic stenosis
- coronary artery disease
- coronary artery bypass grafting
- aortic valve replacement
- percutaneous coronary intervention
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- risk assessment
- aortic valve
- st segment elevation myocardial infarction
- decision making
- cardiovascular events
- acute myocardial infarction
- st elevation myocardial infarction
- antiplatelet therapy
- ejection fraction
- case control
- early onset
- minimally invasive
- left ventricular
- coronary artery bypass
- acute coronary syndrome
- human health
- adipose tissue
- insulin resistance