Antiviral activity of some benzo[g]quinazolines against coxsackievirus B4: biological screening and docking study.
Hatem A AbuelizzAhmed H BakheitMohamed MarzoukWaled M El-SenousyMohamed M AbdellatifGamal A E MostafaQuaiser SaquibSawsan B HassanRashad Al-SalahiPublished in: Pharmacological reports : PR (2023)
The anti coxsackievirus B4 activity has resulted, and the top three active benzoquinazolines (1-3) have bonded to and interacted with the constitutive amino acids in the active region of the multi-target coxsackievirus B4 (RdRp and 3Clpro). Further research is required in the lab. to determine the exact benzoquinazolines mechanism of action.