Gut microbiota and its diet-related activity in children with intestinal failure receiving long-term parenteral nutrition.

Esther G NeelisBarbara A E de KoningJessie M HulstRodanthi PapadopoulouCaroline KerbiriouEdmond H H M RingsRené M H WijnenBen NicholsKonstantinos Gerasimidis

Published in: JPEN. Journal of parenteral and enteral nutrition (2021)

Microbiota composition and its diet-related function are altered in IF, with depletion of beneficial SCFAs and species and supraphysiological increase of potentially harmful pathobionts. The influence of this compositional and functional microbial dysbiosis on patients' outcomes and management warrants further exploration.

Keyphrases

end stage renal disease
physical activity
weight loss
ejection fraction
chronic kidney disease
prognostic factors
microbial community
type diabetes
adipose tissue
patient reported outcomes
metabolic syndrome
glycemic control
genetic diversity