Cancer-Associated Abdominal Vein Thrombosis.
Lorna Muscat-BaronAmber Leigh BorgLaura Maria AttardAlex GattNicoletta RivaPublished in: Cancers (2023)
Cancer is associated with an increased risk of developing venous thromboembolism, due to its direct influence on the three pillars of Virchow's triad (e.g., compression on the blood vessels by the tumour, blood vessels invasion, and cytokine release), together with the effect of exogenous factors (such as chemotherapy, radiotherapy, surgery). In cancer patients, the risk of thrombosis at unusual sites, such as splanchnic, ovarian and renal vein thrombosis, is also increased. Abdominal vein thromboses are frequently incidental findings on abdominal imaging performed as part of the diagnostic/staging workup or the follow-up care of malignancies. There is little evidence on the management of unusual site venous thromboembolism in cancer patients since there are only a few specific recommendations; thus, the management follows the general principles of the treatment of cancer-associated deep vein thrombosis and pulmonary embolism. This narrative review summarises the latest evidence on cancer-associated abdominal vein thrombosis, i.e., thrombosis of the splanchnic, ovarian and renal veins.
Keyphrases
- pulmonary embolism
- venous thromboembolism
- inferior vena cava
- healthcare
- direct oral anticoagulants
- minimally invasive
- high resolution
- palliative care
- lymph node
- squamous cell carcinoma
- clinical practice
- papillary thyroid
- mass spectrometry
- coronary artery bypass
- young adults
- quality improvement
- combination therapy
- surgical site infection
- chronic pain
- childhood cancer