Cord blood antimicrobial peptide LL37 levels in preterm neonates and association with preterm complications.

Zhuxiao RenWenhui MoLiling YangJianlan WangQi ZhangZhicheng ZhongWei WeiZhipeng LiuZhiping WuYao YaoJie Yang

Published in: Italian journal of pediatrics (2022)

Cord blood LL37 levels increased during gestation and decreased after perinatal steroid usage. Very preterm infants who displayed higher cord blood LL37 level had reduced risk of developing BPD. Regulation of pro-inflammatory cytokine IL-6 may be associated with the protective effect of LL37 on BPD.

Keyphrases

cord blood
low birth weight
preterm infants
preterm birth
gestational age
risk factors