Soluble PD-L1 and B7-H4 serum levels during the course of physiological pregnancy.
Pawel MachAngela KöningerBeatrix ReischRainer KimmigAlexandra GellhausPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2022)
The highest serum levels of sPD-L1 in the third trimester suggest increasing suppression of maternal immunity throughout pregnancy, whereas elevated sB7-H4 concentration levels in second trimester suggests different profile of T-cell regulation in physiological pregnancy.