Remote Ischemic Conditioning With Medical Management or Reperfusion Therapy for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.
Qi LiJinxiu GuoHui-Sheng ChenRolf Ankerlund BlauenfeldtDavid C HessFernando PicoPooja KhatriBruce C V CampbellXinggang FengMohamad AbdalKaderJeffrey L SaverRaul Gomes NogueiraBingwu JiangBing LiMin YangHongfei SangQing-Wu YangZhong Ming QiuYi DaiThanh N NguyenPublished in: Neurology (2024)
In patients with ischemic stroke who are not eligible for reperfusion therapy, RIC did not affect mRS functional outcomes but significantly improved the NIHSS score at the follow-up endpoint and reduced stroke recurrence, without increasing the risk of cerebral hemorrhage or death. In patients who received IVT or MT, the benefit of RIC was not observed.
Keyphrases
- acute ischemic stroke
- cerebral ischemia
- subarachnoid hemorrhage
- atrial fibrillation
- brain injury
- blood brain barrier
- healthcare
- ischemia reperfusion injury
- acute myocardial infarction
- heart failure
- acute coronary syndrome
- oxidative stress
- left ventricular
- cell therapy
- percutaneous coronary intervention
- cerebral blood flow