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Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice.

You NiYifan FengDingding ShenMing ChenXiaona ZhuQinming ZhouYining GaoJun LiuQi ZhangYuntian ShenLisheng PengZike ZengDou YinJi HuSheng Chen
Published in: Journal of neuroinflammation (2022)
Overall, our findings indicated an irreversible effect of anti-IgLON5 antibodies and supported the pathogenicity of these antibodies in vivo.
Keyphrases
  • multiple sclerosis
  • type diabetes
  • high fat diet induced
  • metabolic syndrome
  • adipose tissue
  • insulin resistance